| Pheochromocytoma presenting as life-threatening pulmonary edema. | |
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MedLine Citation:
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PMID: 11720247 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute cardiogenic pulmonary edema as the first presentation of pheochromocytoma is uncommon and usually rapidly fatal. A 39-yr-old man presented in acute cardiogenic shock with global ventricular dysfunction that required high-dose iv inotrope support and an intraaortic balloon pump assist device. Abdominal imaging to exclude aortic dissection revealed a 6-cm right adrenal mass. Significant myocardial infarction (electrocardiographic changes and elevated cardiac enzymes) contributed to the cardiac decompensation. After withdrawal of inotrope support, 24-h urinary catecholamine levels revealed 2,155 nmol/d (<125) of adrenaline and 7,437 nmol/d (<560) of noradrenaline, confirming a pheochromocytoma. The tumor was successfully removed at laparotomy; however, the patient's course was complicated by a thromboembolic cerebrovascular accident with paraplegia. He recovered cardiac function almost completely within 3 wk of medical therapy alone. Although uncommon, this case highlights the need to consider pheochromocytoma early in the management of unexplained cardiogenic shock. |
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Authors:
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J Kaye; S Edlin; I Thompson; P J Leedma |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Endocrine Volume: 15 ISSN: 1355-008X ISO Abbreviation: Endocrine Publication Date: 2001 Jul |
Date Detail:
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Created Date: 2001-11-26 Completed Date: 2002-04-04 Revised Date: 2010-06-24 |
Medline Journal Info:
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Nlm Unique ID: 9434444 Medline TA: Endocrine Country: United States |
Other Details:
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Languages: eng Pagination: 203-4 Citation Subset: IM |
Affiliation:
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Department of Endocrinology and Diabetes, Royal Perth Hospital, Western Australia, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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complications,
diagnosis*,
surgery Adult Electrocardiography Epinephrine / urine Humans Male Myocardial Infarction / diagnosis, etiology Norepinephrine / urine Paraplegia / complications Pheochromocytoma / complications, diagnosis*, surgery Pulmonary Edema / etiology* Shock, Cardiogenic / etiology* Stroke / complications Thromboembolism / complications |
| Chemical | |
Reg. No./Substance:
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51-41-2/Norepinephrine; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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