Document Detail


Pheochromocytoma: cyclic attacks of hypertension alternating with hypotension.
MedLine Citation:
PMID:  18094673     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A 52-year-old woman was admitted to hospital with recurrent episodes of chest and abdominal pain, dyspnea, palpitations and diaphoresis. Continuous blood pressure recordings revealed rhythmic alternation between episodes of severe hypertension and episodes of hypotension. This cyclic hemodynamic crisis continued for 2 hours, with each cycle lasting around 15 min. INVESTIGATIONS: Physical examination, electrocardiography, chest radiography, continuous intra-arterial pressure monitoring, blood and urine analysis, echocardiography, abdominal CT and 131I miodobenzylguanidine scanning. DIAGNOSIS: Pheochromocytoma--a catecholamine secreting tumor. MANAGEMENT: Intravenous phentolamine and fluids, oral doxazosin and surgical removal of the tumor.
Authors:
Sergio L Kobal; Esther Paran; Aamer Jamali; Solly Mizrahi; Robert J Siegel; Jonathan Leor
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Nature clinical practice. Cardiovascular medicine     Volume:  5     ISSN:  1743-4300     ISO Abbreviation:  -     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-20     Completed Date:  2008-01-18     Revised Date:  2008-02-07    
Medline Journal Info:
Nlm Unique ID:  101226507     Medline TA:  Nat Clin Pract Cardiovasc Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  53-7     Citation Subset:  IM    
Affiliation:
Department of Surgery A, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
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MeSH Terms
Descriptor/Qualifier:
3-Iodobenzylguanidine / diagnostic use
Administration, Oral
Adrenal Gland Neoplasms / complications,  diagnosis*,  physiopathology,  therapy
Adrenalectomy
Adrenergic alpha-Antagonists / administration & dosage
Antihypertensive Agents / administration & dosage
Blood Chemical Analysis
Blood Pressure*
Blood Pressure Determination
Combined Modality Therapy
Electrocardiography
Female
Fluid Therapy
Heart Rate
Humans
Hypertension / etiology*,  physiopathology,  therapy
Hypotension / etiology*,  physiopathology,  therapy*
Infusions, Intravenous
Middle Aged
Pheochromocytoma / complications,  diagnosis*,  physiopathology,  therapy
Physical Examination
Radiography, Thoracic
Radiopharmaceuticals / diagnostic use
Tomography, X-Ray Computed
Treatment Outcome
Urinalysis
Chemical
Reg. No./Substance:
0/Adrenergic alpha-Antagonists; 0/Antihypertensive Agents; 0/Radiopharmaceuticals; 77679-27-7/3-Iodobenzylguanidine
Comments/Corrections
Comment In:
Nat Clin Pract Cardiovasc Med. 2008 Feb;5(2):E1   [PMID:  18223538 ]

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