Document Detail


Phenylpropanoids from Phragmipedium calurum and their antiproliferative activity.
MedLine Citation:
PMID:  22805176     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Seven stilbenes and one alkylresorcinol were isolated from the orchid Phragmipedium calurum during a screen for anticancer compounds. They were evaluated for antiproliferative activity against multiple human cancer cell lines, and two displayed moderate activity against several cell lines.
Authors:
Courtney M Starks; Russell B Williams; Vanessa L Norman; Julie A Lawrence; Mark O'Neil-Johnson; Gary R Eldridge
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Publication Detail:
Type:  Journal Article     Date:  2012-07-16
Journal Detail:
Title:  Phytochemistry     Volume:  82     ISSN:  1873-3700     ISO Abbreviation:  Phytochemistry     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-08-22     Completed Date:  2013-01-10     Revised Date:  2013-10-17    
Medline Journal Info:
Nlm Unique ID:  0151434     Medline TA:  Phytochemistry     Country:  England    
Other Details:
Languages:  eng     Pagination:  172-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Lead Discovery and Rapid Structure Elucidation Group, Sequoia Sciences, Inc., 1912 Innerbelt Business Center Drive, St. Louis, MO 63114, United States. cstarks@sequoiasciences.com
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / chemistry,  isolation & purification*,  pharmacology*
Cell Line, Tumor
Cell Proliferation / drug effects
Humans
Orchidaceae / chemistry*
Resorcinols / chemistry,  isolation & purification*,  pharmacology*
Stilbenes / chemistry,  isolation & purification*,  pharmacology*
Grant Support
ID/Acronym/Agency:
R43 CA141944/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 0/Resorcinols; 0/Stilbenes; YUL4LO94HK/resorcinol
Comments/Corrections

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