| Phenylboronic acid functionalized gold nanoparticles for highly sensitive detection of Staphylococcus aureus. | |
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MedLine Citation:
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PMID: 22159893 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Herein, we report a phenylboronic acid functionalized gold nanoparticle (GNP)-based colorimetric assay for rapid detection of Staphylococcus aureus (S. aureus) with high sensitivity. In this approach, GNPs can bind to S. aureus by the reaction of phenylboronic acid with the cis-diol configuration in glycans on the bacterial surface, providing a colorimetric readout of the binding event. Using this strategy, we have been able to quantify S. aureus at a concentration of 50 cells per mL (three times the standard deviation divided by the slope of the working curve) in aqueous solution. |
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Authors:
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Jine Wang; Jingqing Gao; Dianjun Liu; Dongxue Han; Zhenxin Wang |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-13 |
Journal Detail:
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Title: Nanoscale Volume: - ISSN: 2040-3372 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101525249 Medline TA: Nanoscale Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China. Liud@ciac.jl.cn(DL) wangzx@ciac.jl.cn(ZW). |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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