Document Detail

Phenothiazine-induced systemic lupus erythematosus with superior vena cava syndrome: case report and review of the literature.
MedLine Citation:
PMID:  3134899     Owner:  NLM     Status:  MEDLINE    
Phenothiazine-induced lupus with circulating anticoagulant (CAC) has been reported infrequently, and is rarely associated with significant symptoms. We describe a patient who we suspect had perphenazine-induced lupus erythematosus with CAC. She had recurrent episodes of venous thrombosis and ultimately developed superior vena cava syndrome. The relationships among phenothiazine-induced lupus, CAC, and thrombosis are discussed.
V D Steen; R Ramsey-Goldman
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  31     ISSN:  0004-3591     ISO Abbreviation:  Arthritis Rheum.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-19     Completed Date:  1988-08-19     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  923-6     Citation Subset:  AIM; IM    
Department of Medicine, University of Pittsburgh School of Medicine, PA 15261.
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MeSH Terms
Anorexia Nervosa / drug therapy
Blood Coagulation Factors / analysis,  immunology
Cardiovascular Diseases / chemically induced
Depression / drug therapy
Lupus Coagulation Inhibitor
Lupus Erythematosus, Systemic / blood,  chemically induced*
Phenothiazines / adverse effects*,  therapeutic use
Vena Cava, Superior*
Reg. No./Substance:
0/Blood Coagulation Factors; 0/Lupus Coagulation Inhibitor; 0/Phenothiazines; 92-84-2/phenothiazine

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