| Phenolic lipid ingredients from cashew nuts. | |
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MedLine Citation:
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PMID: 21735238 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Five new phenolic lipids, 2-(8″Z-eicosenoyl)-6-(8'Z-pentadecenyl) salicylic acid (3), 2-(9″Z-hexadecenoyl)-6-(8'Z, 11'Z-pentadecadienyl) methyl salicylate (5), 2-(10″Z, 13″Z-nonadecadienoyl)-6-(8'Z, 11'Z-pentadecadienyl) salicylic acid (6), 2-(16″Z-pentacosenoyl)-6-(8'Z-pentadecenyl) salicylic acid (7) and 2-(9″Z-octadecenoyl)-6-(8'Z, 11'Z-pentadecadienyl) methyl salicylate (8), and three known compounds, cardols (1), anacardic acid (2) and cardanols (4), were isolated from the nuts of the cashew, Anacardium occidentale L. The structures were established on the basis of detailed MS and NMR spectroscopic analyses. Compound 1 highly enhanced both Th-1 (IL-2, IFN-γ) and Th-2 (IL-4, IL-5) cytokine production, and compounds 7 and 8 highly increased cytokine IL-2 and IFN-γ production in response to concanavalin A in cultured murine Peyer's patch cells ex vivo. The isolated compounds showed moderate inhibitory activities on cytochrome CYP3A4 enzyme. |
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Authors:
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Maorong Suo; Hasegawa Isao; Yoshihiro Ishida; Yasoku Shimano; Changxiao Bi; Hikaru Kato; Fumihide Takano; Tomihisa Ohta |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-7 |
Journal Detail:
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Title: Journal of natural medicines Volume: - ISSN: 1861-0293 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101518405 Medline TA: J Nat Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Venture Business Laboratory, Kanazawa University, Kanazawa, Japan, suomaorong@163.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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