| Phenolic acid metabolites as biomarkers for tea- and coffee-derived polyphenol exposure in human subjects. | |
| | |
MedLine Citation:
|
PMID: 14756917 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Tea and coffee are rich in polyphenols with a variety of biological activities. Many of the demonstrated activities are consistent with favourable effects on the risk of chronic diseases. 4-O-methylgallic acid (4OMGA) and isoferulic acid are potential biomarkers of exposure to polyphenols derived from tea and coffee respectively. 4OMGA is derived from gallic acid in tea, and isoferulic acid is derived from chlorogenic acid in coffee. Our major objective was to explore the relationships of tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid in human subjects. The relationships of long-term usual (111 participants) and contemporaneously recorded current (344 participants) tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid were assessed in two populations. 4OMGA was related to usual (r 0.50, P<0.001) and current (r 0.57, P<0.001) tea intake, and isoferulic acid was related to usual (r 0.26, P=0.008) and current (r 0.18, P<0.001) coffee intake. Overall, our present results are consistent with the proposal that 4OMGA is a good biomarker for black tea-derived polyphenol exposure, but isoferulic acid may be of limited usefulness as a biomarker for coffee-derived polyphenol exposure. |
| | |
Authors:
|
Jonathan M Hodgson; Shin Yee Chan; Ian B Puddey; Amanda Devine; Naiyana Wattanapenpaiboon; Mark L Wahlqvist; Widjaja Lukito; Valerie Burke; Natalie C Ward; Richard L Prince; Kevin D Croft |
Related Documents
:
|
2748997 - The effects of repeated parenteral administration of chelating agents on the distributi... 17093147 - Dietary supplementation with 11trans- and 12trans-18:1 and oxidative stress in humans. 6886297 - Urinary mercapturic acid in chemical workers and in control subjects. 3437597 - Chelation in metal intoxication. xxv: mercaptoacrylic acids as antidotes of lead and ni... 2354147 - Cholesterol interactions with tetracosenoic acid phospholipids in model cell membranes:... 1276227 - Carbodiimide-intermediated esterification of the inorganic phosphates and the effect of... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The British journal of nutrition Volume: 91 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 2004 Feb |
Date Detail:
|
Created Date: 2004-02-03 Completed Date: 2004-03-15 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
|
Languages: eng Pagination: 301-6 Citation Subset: IM |
Affiliation:
|
University of Western Australia School of Medicine and Pharmacology, Royal Perth Hospital, Perth, Western Australia, Australia. jonathan@cyllene.uwa.edu.au |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Biological Markers
/
urine Case-Control Studies Cinnamates / urine Coffee / chemistry* Cross-Sectional Studies Drinking Female Flavonoids / administration & dosage* Gallic Acid / analogs & derivatives*, urine Humans Hydroxybenzoic Acids / metabolism* Male Middle Aged Phenols / administration & dosage* Tea / chemistry* |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Cinnamates; 0/Coffee; 0/Flavonoids; 0/Hydroxybenzoic Acids; 0/Phenols; 0/Tea; 0/polyphenols; 149-91-7/Gallic Acid; 29656-58-4/phenolic acid; 4319-02-2/3,5-dihydroxy-4-methoxybenzoic acid; 537-73-5/isoferulic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of blood sampling schedule and method of calculating the area under the curve on validity and...
Next Document: Factors associated with Hb concentration in children aged 6-59 months in the State of Pernambuco, Br...