| Phenolic Compounds from the Branches of Eucalyptus maideni. | |
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MedLine Citation:
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PMID: 22253109 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Three new phenolic compounds, eucalmaidin F (1), (3S)-5-guaiacyl-3-hydroxypentanoic acid (2), and 8-β-C-glucopyranosyl-5,7-dihydroxy-2-isobutylchromone (3), were isolated from the branches of E. maideni, together with 30 known compounds, including four phenylpropanoids, three lignans, four phloroglucinol glucosides, five dihydroflavonoids, seven simple phenolic compounds, six terpenoids, and glycerol. The new structures were established by spectroscopic studies (MS, and 1D- and 2D-NMR), chemical degradation, and modified Mosher's method. Compounds 3, guaiacylglycerol, 3-hydroxy-1-(4-hydroxyphenyl)propan-1-one, caffeic acid, (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid, (7'S,8R,8'R)-lyoniresinol, (+)-lyoresinol 3α-O-α-L-rhamnopyranoside, garcimangosone, phlorocetophenone 2'-glucopyranoside, (+)-taxifolin 3α-O-α-L-rhamnopyranoside, (+)-aromadendrin, (+)-taxifolin, resveratrol, piceatannol, 3,4,5-trihydroxyphenol. Tachiaside, gallic acid, macrocapals A und G, and oleuropeic acid were evaluated for their cytotoxicities against five human cancer cell lines. Resveratrol, piceatannol, gallic acid, and macrocapal G exhibited moderate inhibitory effects on human myeloid heukemia HL-60 cell, with IC(50) values of 22.05, 22.05, 7.75, and 31.93 μM, respectively; and only macrocapal G showed inhibitory effect on hepatocellular carcinoma SMMC-7721 cell, with an IC(50) value of 26.75 μM. |
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Authors:
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Li-Wen Tian; Min Xu; Yan Li; Xing-Yao Li; Dong Wang; Hong-Tao Zhu; Chong-Ren Yang; Ying-Jun Zhang |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chemistry & biodiversity Volume: 9 ISSN: 1612-1880 ISO Abbreviation: Chem. Biodivers. Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-01-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101197449 Medline TA: Chem Biodivers Country: Switzerland |
Other Details:
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Languages: eng Pagination: 123-30 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich. |
Affiliation:
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State Key Laboratory of Phytochemistry and Plant Resources of West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China, (phone: +86-871-5223235; fax: +86-871-5150124); Graduate University of the Chinese Academy of Sciences, Beijing 100049, P. R. China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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