Document Detail

Phasic Changes in Cell Proliferation in an Autogenous Vein Graft used to Repair the Lacrimal Canaliculus in a Rabbit Model.
MedLine Citation:
PMID:  22399259     Owner:  NLM     Status:  Publisher    
There are few reports that describe the physiological changes in a vein graft used to reconstruct lacrimal canaliculus. This article aims to observe the phasic changes in cell proliferation in an autogenous vein graft used to repair the lacrimal canaliculus. Lacrimal canaliculus disjunction was made in a rabbit model by transecting one side of the lacrimal canaliculus. The injury was repaired using an autogenous ear vein graft. Phasic changes in cell proliferation were observed using reverse transcription polymerase chain reaction and immunohistochemistry for the expression of proliferating cell nuclear antigen in the grafted vein segment. At 3 days postoperative, cell proliferation in the grafted vein segment became active, peaking at 7 days postoperative. Cell proliferation became stable in the epithelium, but remained active in the subepithelial connective tissue at 28 days postoperative. The phasic changes in cell proliferation in the autogenous vein graft were consistent with a normal wound healing response.
Zhigang Li; Yu Zhu
Related Documents :
16533879 - Constitutive integrin activation on tumor cells contributes to progression of leptomeni...
1444889 - Maintenance of amelogenin gene expression by transformed epithelial cells of mouse enam...
6163529 - Specificity of bleomycin-induced cytotoxic effects on ataxia telangiectasia lymphoid ce...
6102619 - Expression of liver phenotypes in cultured mouse hepatoma cells.
10360369 - Guidelines for the characterization and publication of human malignant hematopoietic ce...
11555609 - Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identificatio...
1747249 - A technique for quantitative cytology of nasal secretions.
17703109 - Extracellular matrix induces doxorubicin-resistance in human osteosarcoma cells by supp...
8129039 - Apolipoprotein e localization in human coronary atherosclerotic plaques by in situ hybr...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-7
Journal Detail:
Title:  Journal of reconstructive microsurgery     Volume:  -     ISSN:  1098-8947     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8502670     Medline TA:  J Reconstr Microsurg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Department of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Technical Recommendations for Penile Replantation Based on Lessons Learned from Penile Reconstructio...
Next Document:  Cl anion-dependent Mg-ATPase.