Document Detail

Phase-sensitive inversion recovery single-shot balanced steady-state free precession for detection of myocardial infarction during a single breathhold.
MedLine Citation:
PMID:  18035279     Owner:  NLM     Status:  MEDLINE    
RATIONALE AND OBJECTIVES: We sought to show that phase-sensitive detection and a single-shot technique allow imaging of the heart for detection of myocardial infarction during a single breathhold without adaptation of the inversion time. MATERIALS AND METHODS: Thirty-five patients at 2 weeks to 3 months after Q-wave myocardial infarction were examined on a 1.5-T MR system 10 minutes after the administration of a double-dose extravascular contrast agent. In order to determine the optimal inversion recovery time (TI), a TI scout sequence was performed. An IR-turboFlash sequence with optimized TI was used as standard of reference. A phase-sensitive inversion recovery (PSIR) single-shot TrueFISP sequence, which allows imaging of nine slices during one breathhold (TR/TE/FA/BW: 2.2 ms/1.1 ms/60 degrees , 8 degrees /1220 Hz/Px) was used with a nominal TI of 200 ms. Spatial resolution was identical for both techniques: 1.3 mm x 1.8 mm x 8 mm. Infarct volumes, area of infarction on a selected slice, and scan time for imaging delayed contrast enhancement (DCE) were compared. RESULTS: The mean values for the time of imaging DCE were 10 minutes 43 seconds for the IR turboFLASH and 17 seconds (P<.001) for the PSIR single-shot TrueFISP sequence. No significant difference was found for the mean values of the infarct volumes with 18.7 ml (IR turboFLASH) and 17.3 ml (PSIR single-shot TrueFISP). The values for the correlation coefficients of the infarct volumes and infarct areas of the two different techniques were r=0.95 (P<.004) and r=0.97 (P<.002). The regression equations were y=0.76+0.92*x and y=0.07+0.93*x, respectively. CONCLUSIONS: PSIR single-shot TrueFISP allows for accurate identification of myocardial infarction during a single breathhold with reduction of scan time by a factor of 38.
Armin Huber; Carmel Hayes; Benedikt Spannagl; Johannes Rieber; Volker Klauss; Stefan Oswald Schoenberg; Maximilion Reiser; Bernd Jürgen Wintersperger
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Academic radiology     Volume:  14     ISSN:  1076-6332     ISO Abbreviation:  Acad Radiol     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-23     Completed Date:  2008-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440159     Medline TA:  Acad Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1500-8     Citation Subset:  IM    
Institut für Klinische Radiologie, Klinikum der LMU, Grosshadern, Marchioninistr. 15, 81377 München, Germany.
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MeSH Terms
Contrast Media
Follow-Up Studies
Heart Septum / pathology
Image Enhancement / methods
Image Processing, Computer-Assisted / methods*
Magnetic Resonance Imaging / methods*
Middle Aged
Myocardial Infarction / diagnosis*,  pathology
Myocardium / pathology
Prospective Studies
Time Factors
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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