Document Detail

Pharyngeal lipoma with cartilaginous metaplasia (chondrolipoma): a case report and literature review.
MedLine Citation:
PMID:  9282209     Owner:  NLM     Status:  MEDLINE    
The relative rarity of pharyngeal lipomas and paucity of clinical manifestations in the early stages of tumour growth conspire to task the diagnostic acumen of the clinician. A high index of suspicion and meticulous examination are essential in order to arrive at the diagnosis, which may be achieved pre-operatively by computerized axial tomography, revealing a mass lesion with a characteristic low attenuation value. A case of pharyngeal chondrolipoma in a 25-year-old male is reported. It is suggested that this conceptually intriguing and rarely encountered lesion can be explained on the basis of neoplastic transformation of the second to fourth pharyngeal cleft mesenchymal rests displaying both adipose and cartilaginous differentiation. Alternatively, the cartilage could represent vestigial remnants of non-neoplastic pharyngeal cleft tissue entrapped within a primarily lipomatous neoplasm. Slow growth may occur over a period of several years, prior to overt clinical manifestation.
O G Nwaorgu; E E Akang; B M Ahmad; F N Nwachokor; A N Olu-Eddo
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  111     ISSN:  0022-2151     ISO Abbreviation:  J Laryngol Otol     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-09-15     Completed Date:  1997-09-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  656-8     Citation Subset:  AIM; IM    
Department of Otorhinolaryngology, University College Hospital, Ibadan, Nigeria.
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MeSH Terms
Cartilage / pathology*
Lipoma / pathology*
Metaplasia / pathology
Pharyngeal Neoplasms / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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