Document Detail

Pharmacotherapy in moyamoya disease.
MedLine Citation:
PMID:  2365278     Owner:  NLM     Status:  MEDLINE    
We report a case of characteristic relapsing ischaemic moyamoya disease in a 40-year-old woman. Under polytherapy when she was in a life-threatening condition we observed a prompt, dramatic improvement. Since diagnosis was late a permanent defect could not be prevented. Since corticosteroid medication has been reported as ineffective in the literature and haemodilution and pentoxyfylline seem to be of dubious benefit, we ascribe the dramatic improvement to the calcium antagonist nimodipine. The progress made is in our view equal to the progress made after revascularizing operations. Without a comparable risk, there is hope for treatment that can be initiated earlier in the development of the disease.
J F Spittler; K Smektala
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  [Hokkaido igaku zasshi] The Hokkaido journal of medical science     Volume:  65     ISSN:  0367-6102     ISO Abbreviation:  Hokkaido Igaku Zasshi     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-08-13     Completed Date:  1990-08-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  17410290R     Medline TA:  Hokkaido Igaku Zasshi     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  235-40     Citation Subset:  IM    
Knappschafts Hospital, W. Germany.
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MeSH Terms
Adrenal Cortex Hormones / administration & dosage
Arterial Occlusive Diseases / drug therapy*
Cerebral Angiography
Drug Therapy, Combination
Moyamoya Disease / drug therapy*,  radiography
Nimodipine / administration & dosage,  therapeutic use*
Reg. No./Substance:
0/Adrenal Cortex Hormones; 66085-59-4/Nimodipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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