| Pharmacotherapy for critical limb ischaemia. | |
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MedLine Citation:
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PMID: 11054886 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Critical limb ischaemia involves a severe disturbance of both macrocirculation and microcirculation. Provided revascularisation can be performed (balloon angioplasty, bypass procedures or other reopenings), the major pharmacological problem is to reduce the risk of early thrombosis and midterm hyperplastic growth. Adjuvant treatment for the former is useful, while the latter has not yet found any specific solution. When no technical prerequisites exist for revascularisation, which means extremely deranged vascular morphology, pharmacotherapy can be tried to reduce the specific micro-circulatory events. Results are far from good, though significant reduction of amputations and deaths may be achieved with certain drugs. |
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Authors:
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L Norgren |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Diabetes/metabolism research and reviews Volume: 16 Suppl 1 ISSN: 1520-7552 ISO Abbreviation: Diabetes Metab. Res. Rev. Publication Date: 2000 Sep-Oct |
Date Detail:
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Created Date: 2000-11-28 Completed Date: 2000-11-28 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 100883450 Medline TA: Diabetes Metab Res Rev Country: ENGLAND |
Other Details:
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Languages: eng Pagination: S37-41 Citation Subset: IM |
Copyright Information:
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Copyright 2000 John Wiley & Sons, Ltd. |
Affiliation:
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Department of Vascular Diseases, University Hospital MAS, Malmö, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anticoagulants
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therapeutic use Fibrinolytic Agents / therapeutic use Gene Therapy Hematologic Agents / therapeutic use* Humans Ischemia / drug therapy, surgery, therapy* Leg / blood supply* Platelet Aggregation Inhibitors / therapeutic use Vascular Surgical Procedures |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Fibrinolytic Agents; 0/Hematologic Agents; 0/Platelet Aggregation Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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