Document Detail

Pharmacology of perioperative intraperitoneal and intravenous chemotherapy in patients with peritoneal surface malignancy.
MedLine Citation:
PMID:  23021717     Owner:  NLM     Status:  In-Data-Review    
Peritoneal surface malignancy is a common manifestation of intra-abdominal malignancies. Systemic chemotherapy offers no long-term survival and poor quality of life for these patients in their terminal stages of disease. By contrast, cytoreductive surgery combined with perioperative intraperitoneal and intravenous chemotherapy has resulted in encouraging clinical results. Further improvements should come from both clinical phase II/III studies and pharmacologic research. This article reviews the current pharmacologic data and controversies regarding the perioperative intraperitoneal and intravenous application of chemotherapy.
Kurt Van der Speeten; O Anthony Stuart; Paul H Sugarbaker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgical oncology clinics of North America     Volume:  21     ISSN:  1558-5042     ISO Abbreviation:  Surg. Oncol. Clin. N. Am.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211789     Medline TA:  Surg Oncol Clin N Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  577-97     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Surgical Oncology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, Genk 3600, Belgium; Department of Medicine, Research Group Oncology, University of Hasselt, Hasselt, Belgium. Electronic address:
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