Document Detail

Pharmacological treatment (biotherapy excluded) of peripheral psoriatic arthritis: development of recommendations for clinical practice based on data from the literature and experts opinion.
MedLine Citation:
PMID:  19457691     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To develop recommendations about treatment (except anti-TNF agents) of psoriatic arthritis with peripheral joint involvement (PsA) seen in everyday practice, using evidence from the literature, supplemented with expert opinion when needed. METHODS: The recommendations were based on evidence from the literature. First, a scientific committee used a Delphi procedure to select five focal points of interest. Then, a literature task force looked for relevant publications in the following: Cochrane, Pubmed, and Ovid databases and abstracts from the French Society for Rheumatology, European League against Rheumatism and American College of Rheumatology. Based on the data from these publications, recommendations were drafted and then validated by a group of 68 experts. The strength of each recommendation was determined, as well as the extent of agreement among the experts. RESULTS: The evidence extracted from 73 selected papers was presented to experts during interactive workshops. At the end of the workshops, the experts drafted six recommendations, which were then validated by a final vote including all participants. These six recommendations displayed various strength from B to D. CONCLUSION: These recommendations should help to improve practice uniformity and, ultimately, to improve the management of PsA in France.
Emmanuelle Dernis; Fr??d??ric Lavie; Carine Salliot; Ren??-Marc Flipo; Alain Saraux; Jean-Francis Maillefert; Carle Paul; Philippe Goupille; Alain Cantagrel; Pascal Claudepierre; Philippe Gaudin; Jacques Tebib; Daniel Wendling; Thierry Schaeverbeke; Xavier Le Lo??t; Bernard Combe
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-05-19
Journal Detail:
Title:  Joint, bone, spine : revue du rhumatisme     Volume:  76     ISSN:  1778-7254     ISO Abbreviation:  Joint Bone Spine     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-26     Completed Date:  2010-01-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100938016     Medline TA:  Joint Bone Spine     Country:  France    
Other Details:
Languages:  eng     Pagination:  524-31     Citation Subset:  IM    
Service de Rhumatologie, Centre Hospitalier, Le Mans, France.
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MeSH Terms
Advisory Committees
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Antirheumatic Agents / therapeutic use
Arthritis, Psoriatic / diagnosis,  drug therapy*
Azathioprine / therapeutic use
Evidence-Based Medicine / methods
Expert Testimony
Follow-Up Studies
Glucocorticoids / therapeutic use
Hospitals, Teaching
Isoxazoles / therapeutic use
Joints / pathology
Practice Guidelines as Topic
Randomized Controlled Trials as Topic
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Antirheumatic Agents; 0/Glucocorticoids; 0/Isoxazoles; 0/Placebos; 446-86-6/Azathioprine; 75706-12-6/leflunomide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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