| Pharmacological properties of traditional medicines (XXVII). Interaction between Ephedra Herb and Gypsum under hyperthermal conditions in rats. | |
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MedLine Citation:
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PMID: 12132660 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There are many important considerations in the interactions among the herbal constituents in a prescription of traditional Chinese medicine (TCM). Ephedra Herb [Chinese characters: see text] (Eph) is described a warm and acrid agent in TCM. The combination of Eph and Gypsum [Chinese characters: see text] (Eph-Gyp) shows specific actions in patients with different body temperatures. Previous reports suggested that Gypsum prevents the thermogenesis effect induced by ephedrine at an ambient temperature of 22 degrees C. In this investigation, the properties of Eph-Gyp in hyperthermal rats were studied in detail. It was shown that Gypsum Extract (GyE) enhanced the thermogenesis of Eph in hyperthermal rats, although not in normal rats. The results support not only the opposite actions of Eph-GyE but also the clinical differences in the symptomatic patterns of body temperature for Makyo-Kanseki-To [Chinese characters: see text] and Dai-Seiryu-To [Chinese characters: see text]. |
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Authors:
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Dan Yuan; Hiroshi Sunouchi; Tetsurou Sakurai; Ken-ichi Saito; Yoshihiro Kano |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biological & pharmaceutical bulletin Volume: 25 ISSN: 0918-6158 ISO Abbreviation: Biol. Pharm. Bull. Publication Date: 2002 Jul |
Date Detail:
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Created Date: 2002-07-22 Completed Date: 2003-01-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9311984 Medline TA: Biol Pharm Bull Country: Japan |
Other Details:
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Languages: eng Pagination: 872-4 Citation Subset: IM |
Affiliation:
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Department of Traditional Chinese Medicinal Sciences, Shenyang Pharmaceutical University, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amygdalin
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pharmacology*,
therapeutic use Animals Disease Models, Animal Drug Combinations Drug Interactions Drugs, Chinese Herbal / pharmacology*, therapeutic use Ephedra / chemistry* Ephedrine / pharmacology*, therapeutic use Fever / drug therapy* Male Medicine, Chinese Traditional* Plant Extracts / pharmacology*, therapeutic use Rats Rats, Wistar Thermogenesis / drug effects* Thermography |
| Chemical | |
Reg. No./Substance:
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0/Drug Combinations; 0/Drugs, Chinese Herbal; 0/Plant Extracts; 0/makyokansekito; 29883-15-6/Amygdalin; 299-42-3/Ephedrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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