Document Detail

Pharmacological management of postoperative ileus.
MedLine Citation:
PMID:  19399212     Owner:  NLM     Status:  MEDLINE    
The duration of postoperative ileus following abdominal surgery is quite variable, and prolonged postoperative ileus is an iatrogenic phenomenon with important influence on patient morbidity, hospital costs and length of stay in hospital. Adequate treatment for prolonged postoperative ileus is important to improve patient morbidity and clinical efficiency. Both clinical and pharmacological management strategies have improved rapidly over the last decade, and appropriate and timely management using multimodal techniques should be used for optimal care. In this review, we define postoperative ileus, describe the pathogenesis and briefly discuss clinical management before detailing potential pharmacologic management options.
Farhad Zeinali; Jonah J Stulberg; Conor P Delaney
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Canadian journal of surgery. Journal canadien de chirurgie     Volume:  52     ISSN:  1488-2310     ISO Abbreviation:  Can J Surg     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-28     Completed Date:  2009-05-21     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  0372715     Medline TA:  Can J Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  153-7     Citation Subset:  IM    
Department of Surgery, University Hospitals Case Medical Center, Cleveland, Ohio 44106-5047, USA.
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MeSH Terms
Adrenergic alpha-Antagonists / therapeutic use
Adrenergic beta-Antagonists / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Bisacodyl / therapeutic use
Cathartics / therapeutic use
Cisapride / therapeutic use
Dihydroergotamine / therapeutic use
Ileus / drug therapy*,  physiopathology
Inflammation / drug therapy
Naltrexone / analogs & derivatives,  therapeutic use
Neostigmine / therapeutic use
Parasympathomimetics / therapeutic use
Piperidines / therapeutic use
Postoperative Complications / drug therapy*
Propranolol / therapeutic use
Quaternary Ammonium Compounds / therapeutic use
Receptors, Opioid, mu / antagonists & inhibitors
Serotonin Receptor Agonists / therapeutic use
Reg. No./Substance:
0/Adrenergic alpha-Antagonists; 0/Adrenergic beta-Antagonists; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Cathartics; 0/Parasympathomimetics; 0/Piperidines; 0/Quaternary Ammonium Compounds; 0/Receptors, Opioid, mu; 0/Serotonin Receptor Agonists; 16590-41-3/Naltrexone; 511-12-6/Dihydroergotamine; 525-66-6/Propranolol; 59-99-4/Neostigmine; 603-50-9/Bisacodyl; 677C126AET/alvimopan; 81098-60-4/Cisapride; 83387-25-1/methylnaltrexone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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