Document Detail


Pharmacological and clinical differences between low-molecular-weight heparins: implications for prescribing practice and therapeutic interchange.
MedLine Citation:
PMID:  20221326     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Thanks to their predictable pharmacokinetics and ease of use, low-molecular-weight heparins (LMWHs) have established uses in the prevention and treatment of thrombotic diseases and as a replacement for unfractionated heparin (UFH). Although LMWHs as a class have similar antithrombotic effects, they comprise a diverse group of agents with distinct biochemical and pharmacological profiles. In light of the ongoing pressure to contain pharmacy costs, the diversity among the LMWHs and their benefits over UFH are important considerations in clinical practice.
Authors:
Geno J Merli; James B Groce
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  P & T : a peer-reviewed journal for formulary management     Volume:  35     ISSN:  1052-1372     ISO Abbreviation:  P T     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-11     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  9015516     Medline TA:  P T     Country:  United States    
Other Details:
Languages:  eng     Pagination:  95-105     Citation Subset:  -    
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