| The pharmacological management of intrahepatic cholestasis of pregnancy. | |
MedLine Citation:
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PMID: 21352094 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intrahepatic cholestasis of pregnancy is the most common liver disease occurring in the second half of pregnancy, characterized by pruritus and elevated serum bile acids often coupled to abnormal liver tests. Maternal prognosis is favourable with a complete symptom resolution after delivery, while preterm deliveries, fetal respiratory distress and stillbirths may occur. The goal of the pharmacological treatment of the disease is to improve maternal symptoms and biochemical alterations and, most importantly, to reduce fetal adverse events.The present manuscript will review the current knowledge on the pharmacological treatment of intrahepatic cholestasis of pregnancy. |
Authors:
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Francesco Azzaroli; Laura Turco; Andrea Lisotti; Claudio Calvanese; Giuseppe Mazzella |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current clinical pharmacology Volume: 6 ISSN: 1574-8847 ISO Abbreviation: Curr Clin Pharmacol Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-03-09 Completed Date: 2011-06-20 Revised Date: 2011-09-06 |
Medline Journal Info:
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Nlm Unique ID: 101273158 Medline TA: Curr Clin Pharmacol Country: United Arab Emirates |
Other Details:
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Languages: eng Pagination: 12-7 Citation Subset: IM |
Affiliation:
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Department of Clinical Medicine, Gastroenterology Unit, St. Orsola-Malpighi Hospitali, University of Bologna, Italy. francesco.azzaroli@unibo.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bile Acids and Salts / blood Cholestasis, Intrahepatic / drug therapy*, etiology, physiopathology Female Humans Liver Function Tests Pregnancy Pregnancy Complications / drug therapy*, physiopathology Pregnancy Outcome / epidemiology* Prognosis Pruritus / etiology |
| Chemical | |
Reg. No./Substance:
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0/Bile Acids and Salts |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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