Document Detail


Pharmacologic radionuclide myocardial perfusion imaging.
MedLine Citation:
PMID:  12493156     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pharmacologic stress testing with myocardial perfusion imaging has enabled patients who cannot complete adequate exercise to undergo diagnostic and prognostic evaluation for coronary artery disease. Pharmacologic stress agents belong to two groups: vasodilators (such as adenosine and dipyridamole), and inotropes (such as dobutamine). All have similar sensitivity (89%-91%) and specificity (78%-86%) for the diagnosis of coronary disease. For risk stratification, the risk of future cardiac events is related to the extent and severity of perfusion abnormalities. Pharmacologic stress testing permits risk stratification as early as 1 to 4 days following an acute myocardial infarction, and is superior to exercise stress testing in this regard. Similarly, it identifies patients at high risk for perioperative cardiac events prior to noncardiac surgery. This review summarizes the current evidence available regarding the diagnostic and prognostic use of pharmacologic stress testing.
Authors:
Sachin M Navare; Athanasios Kapetanopoulos; Gary V Heller
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current cardiology reports     Volume:  5     ISSN:  1523-3782     ISO Abbreviation:  Curr Cardiol Rep     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2002-12-20     Completed Date:  2003-05-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100888969     Medline TA:  Curr Cardiol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  16-24     Citation Subset:  IM    
Affiliation:
University of Connecticut School of Medicine, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102, USA.
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MeSH Terms
Descriptor/Qualifier:
Coronary Artery Disease / physiopathology,  radionuclide imaging*
Coronary Circulation / physiology
Exercise Test*
Humans
Perfusion*
Prognosis
Radionuclide Imaging*
Risk Assessment

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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