| [Pharmacologic measures for the prevention of mechanical ventilation-associated pneumonia]. | |
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MedLine Citation:
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PMID: 20022067 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ventilator associated pneumonia is the principal infectious complication in the Intensive Care Unit (ICU), and represents the main infectious cause of morbidity and mortality. Its diagnosis and management is complex. Consequently, its prevention becomes a cornerstone in daily clinical practice. Daily interruption of sedation, oral and digestive decontamination, prophylactic administration of systemic and/or inhaled antibiotics, glycemic control, stress ulcer prophylaxis, transfusion policy and timing and adequacy of antibiotic treatment are the main suggested pharmacologic interventions. The aim of this review is to critically describe the principal pharmacologic interventions for the prevention of ventilator associated pneumonia, focusing on the degree of the evidence and the appropriateness for daily clinical practice. |
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Authors:
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Marta Ulldemolins; Marcos I Restrepo; Jordi Rello |
Publication Detail:
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Type: English Abstract; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2010-12-03 |
Journal Detail:
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Title: Medicina clínica Volume: 136 ISSN: 0025-7753 ISO Abbreviation: Med Clin (Barc) Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-18 Completed Date: 2011-04-21 Revised Date: 2011-09-19 |
Medline Journal Info:
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Nlm Unique ID: 0376377 Medline TA: Med Clin (Barc) Country: Spain |
Other Details:
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Languages: spa Pagination: 21-5 Citation Subset: IM |
Copyright Information:
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Copyright © 2009 Elsevier España, S.L. All rights reserved. |
Affiliation:
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Servicio de Medicina Intensiva, Hospital Universitario de Tarragona Joan XXIII, Instituto de Investigación Sanitaria Pere Virgili (IISPV), Tarragona, Spain. |
Vernacular Title:
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Medidas farmacológicas para la prevención de la neumonía asociada a la ventilación mecánica. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Buccal Administration, Inhalation Anti-Bacterial Agents / administration & dosage* Anti-Infective Agents, Local / administration & dosage* Erythrocyte Transfusion / utilization Gastrointestinal Tract / microbiology Humans Hypnotics and Sedatives / administration & dosage Hypoglycemic Agents / administration & dosage Injections, Intravenous Mouth / microbiology Pneumonia, Ventilator-Associated / prevention & control* Stomach Ulcer / prevention & control Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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KL2 RR025766/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Anti-Infective Agents, Local; 0/Hypnotics and Sedatives; 0/Hypoglycemic Agents |
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