| Pharmacologic evaluation of cardiovascular reflex responses in migraine patients: lack of central sympathetic modulation? | |
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MedLine Citation:
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PMID: 2620855 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To characterize autonomic imbalance in migraine, we compared the cardiovascular reflex responses of 10 migraineurs and 10 healthy subjects after pharmacological noradrenergic stimulation or inhibition. A battery of 5 autonomic tests was administered on basal conditions as well as after pretreatment with drugs acting at different levels on the noradrenergic pathway: pseudoephedrine, clonidine, guanethidine, indenolol, prazosin. Our data confirm a predominantly sympathetic hypofunction in migraine and provide evidence for an impairment of the central autonomic control. |
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Authors:
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L Munari; I Milanesi; A Silvani; G Bussone; A Boiardi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Functional neurology Volume: 4 ISSN: 0393-5264 ISO Abbreviation: Funct. Neurol. Publication Date: 1989 Oct-Dec |
Date Detail:
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Created Date: 1990-03-28 Completed Date: 1990-03-28 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8707746 Medline TA: Funct Neurol Country: ITALY |
Other Details:
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Languages: eng Pagination: 375-8 Citation Subset: IM |
Affiliation:
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Neurologic Institute C. Besta, Milan, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cardiovascular System / physiopathology* Central Nervous System / physiopathology Female Humans Male Migraine Disorders / physiopathology* Sympathetic Nervous System / physiopathology* |
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