Document Detail

Pharmacologic approaches to musculoskeletal disorders.
MedLine Citation:
PMID:  3288328     Owner:  NLM     Status:  MEDLINE    
Pharmacologic considerations of musculoskeletal disease in the elderly involve an appreciation of the pathophysiology of aging as it alters host response to the particular drugs used for these disorders. Treatment of rheumatic conditions is often chronic. Pharmacologic studies of drug handling in the elderly versus the young are often short term and not appropriate to the answers required for sustained therapy in aging individuals with decremental organ system decline, dysfunction, and disease. Where inadequate information exists, the clinical therapist must proceed cautiously on a highly individualized basis in choice of agents, use of those agents at whatever particular dose, and monitoring to ensure safety. Such commitment requires the best of the art as well as the science of medicine. No less is required in the appropriate therapy of these disorders in our elderly population.
S H Roth
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in geriatric medicine     Volume:  4     ISSN:  0749-0690     ISO Abbreviation:  Clin. Geriatr. Med.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-07-28     Completed Date:  1988-07-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8603766     Medline TA:  Clin Geriatr Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  441-61     Citation Subset:  IM    
Harrington Arthritis Research Center, Phoenix, Arizona.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Analgesics / pharmacokinetics,  therapeutic use
Anti-Inflammatory Agents / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / adverse effects,  pharmacokinetics,  therapeutic use
Bone Diseases / drug therapy*
Drug Therapy, Combination
Muscular Diseases / drug therapy*
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Analgesics; 0/Anti-Inflammatory Agents; 0/Anti-Inflammatory Agents, Non-Steroidal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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