Document Detail


Pharmacologic approaches to management of arrhythmias in patients with cardiomyopathy and heart failure.
MedLine Citation:
PMID:  3314443     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Interactions between disordered cardiac rhythm and abnormal cardiac hemodynamic function are well recognized. Demonstrations of this relationship include the relationship between prognostic significance of ventricular ectopy and left ventricular ejection fraction, impairment of ventricular function in association with loss of atrial systole in disease states, increased risk of potentially lethal arrhythmias in the myopathic ventricle, and the evolution of advanced grades of ventricular arrhythmias in acute heart failure. With the development of newer and more potent antiarrhythmic agents, in conjunction with drugs that can improve the failing circulation, it is now possible to clarify these interrelationships and perhaps develop new strategies for clinical management.
Authors:
R J Myerburg; K M Kessler; L Zaman; P Fernandez; E DeMarchena; A Castellanos
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  American heart journal     Volume:  114     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1987-11-30     Completed Date:  1987-11-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1273-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, University of Miami Medical Center, FL.
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MeSH Terms
Descriptor/Qualifier:
Anti-Arrhythmia Agents / therapeutic use*
Arrhythmias, Cardiac / drug therapy*
Cardiomyopathy, Dilated*
Heart Failure*
Humans
Grant Support
ID/Acronym/Agency:
HL-07636/HL/NHLBI NIH HHS; HL-28130/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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