Document Detail


Pharmacokinetics during pregnancy and delivery.
MedLine Citation:
PMID:  7076341     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pharmacokinetics of certain drugs were studied in the following patient groups: in women in stage III of pregnancy, in women in labor, and in non-pregnant women as a control group. In late gravidity several parameters of distribution and elimination change. Nevertheless, it is not necessary to modify the usual dose schedule. However, sulfonamides and antibiotics should be administered in the upper range of dosage. In contrast to late pregnancy, we found elimination of drugs to be always retarded during labor. Attention must be paid to accumulation, which may occur.
Authors:
H Nöschel; G Peiker; B Müller; S Schröder; A Bonow; P Meinhold; R Voigt; R Tittel
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of biological research in pregnancy     Volume:  3     ISSN:  0173-8593     ISO Abbreviation:  Int J Biol Res Pregnancy     Publication Date:  1982  
Date Detail:
Created Date:  1982-07-22     Completed Date:  1982-07-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8011123     Medline TA:  Int J Biol Res Pregnancy     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  66-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Female
Half-Life
Humans
Kinetics
Labor, Obstetric*
Pharmaceutical Preparations / metabolism*
Pregnancy*
Pregnancy Trimester, Third
Chemical
Reg. No./Substance:
0/Pharmaceutical Preparations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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