| Pharmacokinetics of aspirin and chloramphenicol in normal and leprotic patients before and after dapsone therapy. | |
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MedLine Citation:
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PMID: 3403099 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pharmacokinetics of aspirin and chloramphenicol was studied in 16 normal and 16 patients suffering from leprosy. A significant increase (p less than 0.05) in the elimination half-life of chloramphenicol was observed before and after dapsone treatment in leprotic patients as compared with the normal volunteers, while no significant difference was observed in any of the pharmacokinetic parameters with aspirin. |
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Authors:
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S K Garg; B Kumar; V K Shukla; V Bakaya; R Lal; S Kaur |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of clinical pharmacology, therapy, and toxicology Volume: 26 ISSN: 0174-4879 ISO Abbreviation: Int J Clin Pharmacol Ther Toxicol Publication Date: 1988 Apr |
Date Detail:
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Created Date: 1988-09-20 Completed Date: 1988-09-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8003415 Medline TA: Int J Clin Pharmacol Ther Toxicol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 204-5 Citation Subset: IM |
Affiliation:
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Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aspirin / pharmacokinetics* Chloramphenicol / pharmacokinetics* Dapsone / adverse effects*, therapeutic use Drug Interactions Female Half-Life Humans Leprosy / drug therapy, metabolism* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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50-78-2/Aspirin; 56-75-7/Chloramphenicol; 80-08-0/Dapsone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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