| Pharmacokinetic profile in late pregnancy and cord blood concentration of tipranavir and enfuvirtide. | |
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MedLine Citation:
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PMID: 21571982 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The data on the use of tipranavir and enfuvirtide in pregnancy are very limited. We performed a pharmacokinetic profile in a pregnant woman with multidrug-resistant HIV-1 infection at 37 weeks gestation. Tipranavir levels were in the therapeutic range and the cord blood concentration at delivery was relatively high when compared with other protease inhibitors. No enfuvirtide was detected in the fetal compartment. Tipranavir and enfuvirtide were successfully used in pregnancy, but possible toxicities must be kept in mind. |
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Authors:
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K Weizsaecker; M Kurowski; B Hoffmeister; D Schürmann; C Feiterna-Sperling |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of STD & AIDS Volume: 22 ISSN: 1758-1052 ISO Abbreviation: Int J STD AIDS Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9007917 Medline TA: Int J STD AIDS Country: England |
Other Details:
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Languages: eng Pagination: 294-5 Citation Subset: IM; X |
Affiliation:
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Department of Obstetrics, Charité Universitätsmedizin Berlin. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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