| Pharmacokinetic factors in the clinical use of tryptophan. | |
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MedLine Citation:
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PMID: 6512006 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A patient with chronic pain and DSM-III unipolar and cyclothymic disorders was treated with L-tryptophan, 3000 mg before bed for 3 nights, and showed no response. She then began to take L-tryptophan, 1000 mg every 4 hours, with a high carbohydrate, low protein meal and immediately showed a clear improvement in exercise tolerance (reduced pain) and alleviation of affective symptoms. The importance of pharmacokinetic factors in the clinical use of L-tryptophan is emphasized. |
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Authors:
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R J Hedaya |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of clinical psychopharmacology Volume: 4 ISSN: 0271-0749 ISO Abbreviation: J Clin Psychopharmacol Publication Date: 1984 Dec |
Date Detail:
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Created Date: 1985-01-31 Completed Date: 1985-01-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8109496 Medline TA: J Clin Psychopharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 347-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chronic Disease Cyclothymic Disorder / drug therapy Depressive Disorder / drug therapy Diet Female Half-Life Humans Kinetics Pain / drug therapy Tryptophan / administration & dosage, metabolism, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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73-22-3/Tryptophan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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