Document Detail


Pharmacokinetic analysis of neoplasms using contrast-enhanced dynamic magnetic resonance imaging.
MedLine Citation:
PMID:  10551628     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pharmacokinetic analysis using dynamic magnetic resonance imaging provides insight into various physiological aspects of tumors, including capillary wall permeability and the volume of the interstitial space. This physiology may be investigated in either a heuristic or model-based fashion using various methods presented in the literature. This review describes many of these approaches and provides some guidelines for those intending to use dynamic magnetic resonance imaging in the investigation of neoplasms.
Authors:
G J Parker; P S Tofts
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Topics in magnetic resonance imaging : TMRI     Volume:  10     ISSN:  0899-3459     ISO Abbreviation:  Top Magn Reson Imaging     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-11-24     Completed Date:  1999-11-24     Revised Date:  2011-11-03    
Medline Journal Info:
Nlm Unique ID:  8913523     Medline TA:  Top Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  130-42     Citation Subset:  IM    
Affiliation:
NMR Research Unit, Institute of Neurology, University College London, United Kingdom. g.parker@ion.ucl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Contrast Media / administration & dosage,  pharmacokinetics*
Dose-Response Relationship, Drug
Humans
Magnetic Resonance Imaging / methods*,  trends
Neoplasms / diagnosis*,  metabolism
Sensitivity and Specificity
Time Factors
Grant Support
ID/Acronym/Agency:
491//Multiple Sclerosis Society
Chemical
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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