Document Detail


Pharmacogenomics and patient care: one size does not fit all.
MedLine Citation:
PMID:  23019654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The time is ripe to assess whether pharmacogenomics research--the study of the genetic basis for variation in drug response--has provided important insights into a personalized approach to prescribing and dosing medications. Here, we describe the status of the field and approaches for addressing some of the open questions in pharmacogenomics research and use of genetic testing in guiding drug therapy.
Authors:
Kathleen M Giacomini; Sook Wah Yee; Mark J Ratain; Richard M Weinshilboum; Naoyuki Kamatani; Yusuke Nakamura
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Science translational medicine     Volume:  4     ISSN:  1946-6242     ISO Abbreviation:  Sci Transl Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-28     Completed Date:  2013-07-30     Revised Date:  2014-03-27    
Medline Journal Info:
Nlm Unique ID:  101505086     Medline TA:  Sci Transl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  153ps18     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Drug Prescriptions
Genetic Variation
Humans
Individualized Medicine
Patient Care*
Pharmacogenetics*
Translational Medical Research
Grant Support
ID/Acronym/Agency:
GM061393/GM/NIGMS NIH HHS; GM61388/GM/NIGMS NIH HHS; GM61390/GM/NIGMS NIH HHS; U01 GM061390/GM/NIGMS NIH HHS; U01 GM061393/GM/NIGMS NIH HHS; U19 GM061388/GM/NIGMS NIH HHS; U19 GM061390/GM/NIGMS NIH HHS
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