| Pharmacogenetics in reproductive and perinatal medicine. | |
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MedLine Citation:
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PMID: 20017673 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The clinical application of pharmacogenetics has been well accepted by some medical specialties, but not all. The aim of this review is to discuss the current use of pharmacogenetics in reproductive and perinatal medicine and to highlight areas where pharmacogenetics may be able to help in the future to predict response to medicines in terms of efficacy and safety. This applies to drugs that are specific to pregnancy and reproduction, as well as drugs prescribed for the treatment of medical disorders in pregnancy. Our review points out the need for well-designed clinical studies on the efficacy and safety of medicines used in women of childbearing age in order to define the additional utility provided by pharmacogenetic testing. |
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Authors:
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Ana Alfirevic; Zarko Alfirevic; Munir Pirmohamed |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Pharmacogenomics Volume: 11 ISSN: 1744-8042 ISO Abbreviation: Pharmacogenomics Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-18 Completed Date: 2010-03-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100897350 Medline TA: Pharmacogenomics Country: England |
Other Details:
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Languages: eng Pagination: 65-79 Citation Subset: IM |
Affiliation:
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Department of Pharmacology & Therapeutics, Sherrington Building, Ashton Street, University of Liverpool, Liverpool, Merseyside, L69 3GE, UK. Ana.Alfirevic@liv.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Betamethasone
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therapeutic use Dexamethasone / therapeutic use Female Fetus / drug effects Folic Acid / metabolism, therapeutic use Humans Infant, Newborn Lung / drug effects, embryology Ovary / drug effects Perinatal Care* Pharmacogenetics* Pre-Eclampsia / drug therapy Pregnancy / drug effects Reproductive Medicine* Tocolysis |
| Chemical | |
Reg. No./Substance:
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378-44-9/Betamethasone; 50-02-2/Dexamethasone; 59-30-3/Folic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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