Document Detail


Pharmacogenetics of the arylamine N-acetyltransferases: a symposium in honor of Wendell W. Weber.
MedLine Citation:
PMID:  11095579     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article is a report on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics presented at the joint meeting of the American Society for Biochemistry and Molecular Biology and the American Society for Pharmacology and Experimental Therapeutics, June 4-8, Boston, Massachusetts. The presentations focused on the pharmacogenetics of the NAT1 and NAT2 arylamine N-acetyltransferases, including developmental regulation, structure-function relationships, and their possible role in susceptibility to breast, colon, and pancreatic cancers. The symposium honored Wendell W. Weber for over 35 years of leadership and scientific advancement in pharmacogenetics and was highlighted by his overview of the historical development of the field.
Authors:
D W Hein; C A McQueen; D M Grant; G H Goodfellow; F F Kadlubar; W W Weber
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Publication Detail:
Type:  Congresses; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Drug metabolism and disposition: the biological fate of chemicals     Volume:  28     ISSN:  0090-9556     ISO Abbreviation:  Drug Metab. Dispos.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-02-02     Completed Date:  2001-02-02     Revised Date:  2008-01-17    
Medline Journal Info:
Nlm Unique ID:  9421550     Medline TA:  Drug Metab Dispos     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1425-32     Citation Subset:  IM    
Affiliation:
Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky, USA. d.hein@louisville.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Arylamine N-Acetyltransferase / genetics*,  metabolism*
Humans
Neoplasms / enzymology,  genetics
Pharmacogenetics*
Grant Support
ID/Acronym/Agency:
CA-34627/CA/NCI NIH HHS; ES09812/ES/NIEHS NIH HHS; ES10047/ES/NIEHS NIH HHS; R01 CA034627-15/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
EC 2.3.1.5/Arylamine N-Acetyltransferase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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