Document Detail


Pharmacogenetic principles in the Hippocratic writings.
MedLine Citation:
PMID:  16239353     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-five centuries after Hippocrates, we are at the beginning of an era of individualized, molecular, and genomic medicine, where diagnosis, prognosis, and treatment will be increasingly based on our understanding of the human organism's genetic and molecular composition. The most difficult task in this process has proven to be the application of the scientific advancements to the clinical setting, and clinical pharmacology is an essential discipline in this translational process. This article traces the roots of the emerging personalized and genome-based medicine to the teachings of Hippocrates.
Authors:
Gerasimos P Sykiotis; George D Kalliolias; Athanasios G Papavassiliou
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Publication Detail:
Type:  Historical Article; Journal Article    
Journal Detail:
Title:  Journal of clinical pharmacology     Volume:  45     ISSN:  0091-2700     ISO Abbreviation:  J Clin Pharmacol     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-21     Completed Date:  2006-04-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0366372     Medline TA:  J Clin Pharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1218-20     Citation Subset:  IM    
Affiliation:
Department of Biomedical Genetics, University of Rochester Medical Center, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Drug Therapy
Genetic Predisposition to Disease
Greek World
History, Ancient
Humans
Pharmacogenetics*
Philosophy, Medical / history*

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