| Pharmacoepidemiology in the Postmarketing Assessment of the Safety and Efficacy of Drugs in Older Adults. | |
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MedLine Citation:
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PMID: 21653991 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Much of the information on safety and efficacy of drugs in older people is obtained after marketing. Pharmacoepidemiologic studies play an increasing role in obtaining this information. Pharmacoepidemiologic studies contribute significantly to knowledge of risks associated with medicines in older people and less so to that of benefits. Recent improvements in methodology in both pharmacoepidemiology and geriatric medicine have improved the validity and reduced the bias of these studies. Pharmacoepidemiologic studies are a critical component of assessing the risks of medicines in older people. Where possible, findings of pharmacoepidemiologic studies should be tested with well-conducted interventional randomized trials in relevant populations of older people. |
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Authors:
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Sarah N Hilmer; Danijela Gnjidic; Darrell R Abernethy |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-8 |
Journal Detail:
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Title: The journals of gerontology. Series A, Biological sciences and medical sciences Volume: - ISSN: 1758-535X ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-6-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9502837 Medline TA: J Gerontol A Biol Sci Med Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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MBBS, Clinical Pharmacology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia. shilmer@med.usyd.edu.au. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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