| [Pharmacoeconomy in acne--evaluation of benefit and economics]. | |
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MedLine Citation:
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PMID: 20482687 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Acne belongs to the most common skin diseases and has a prevalence in the adolescence of nearly 100% and in adults of about 4%. The quality of life indes is significantly reduced und has impact on daily activities and social life and physical and psychological well being as well. The socioeconomic relevance is based not only on its prevalence but on direct and indirect costs. For acne therapy the knowledge on therapeutic costs is of importance but the cost benefit ratio as well. GOAL: Evidence of therapeutic costs in acne and economic benefit of the therapy. METHODS: Systematic review of Cochrane data. RESULTS: Calculations reveal general costs of acne treatment in Germany over 400 Mill.Euro per year. For the treatment with topical retinoids, BPO and antibiotics as well as systemic drugs only a few studies on costeffectiveness are available. For topical treatments results are not conclusive and dependent on the different health systems. New topical combinations may have a better economic outcome, however, more studies are needed. With regard to systemic therapies of moderate to severe acne based on the international references the costbenefit ratio favours the treatment with oral isotretinoin on the longterm outcome. Superiority is based on the relationship of costs and clinical outcome and the increased quality of life as well (cost-benefit ratio). It has to be emphazised that only longterm observations over years will lead to a valid calculation of costs and benefit. FACIT: Taking the high social and quality of life impact into consideration an early, well targeted and effective therapy is prevailing. Initial higher cost are balanced by a high quality of outcome under experienced dermatological supervision. The patients benefit is ranked over the final costs because of its medical, social and ethical aspects. To sample more differentiated data on pharmacoeconomic aspects well designed new clinical studies are to be set up. |
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Authors:
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Marc A Radtke; Ines Schäfer; Matthias Augustin |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG Volume: 8 Suppl 1 ISSN: 1610-0387 ISO Abbreviation: J Dtsch Dermatol Ges Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-05-20 Completed Date: 2010-10-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101164708 Medline TA: J Dtsch Dermatol Ges Country: Germany |
Other Details:
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Languages: ger Pagination: S105-14 Citation Subset: IM |
Affiliation:
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Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Dermatologie und Venerologie, Hamburg Competenzzentrum Versorgungsforschung in der Dermatologie CVderm. m.radtke@uke.uni-hamburg.de |
Vernacular Title:
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Pharmakoökonomie der Akne--Bewertung von Nutzen und Wirtschaftlichkeit. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acne Vulgaris
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drug therapy*,
economics*,
epidemiology,
psychology Adolescent Adult Child Cost-Benefit Analysis Cross-Sectional Studies Drug Costs / statistics & numerical data* Germany Humans National Health Programs / economics* Quality of Life / psychology Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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