| Pharmacoeconomics of Alzheimer's disease (AD) treatment with cholinesterase inhibitors. | |
| | |
MedLine Citation:
|
PMID: 22476975 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Until more effective and especially disease-modifying treatments for Alzheimer's disease (AD) are available, the therapeutic arsenal consists of cholinesterase inhibitors for mild to moderate dementia and memantine for moderate to severe dementia. Health economic data make an important contribution to the planning of healthcare services and the estimation of the cost of drug reimbursement. As such, for cholinesterase inhibitors it is claimed that the direct cost of the drug itself is eclipsed by the cost savings associated with delaying institutionalisation or delaying the time of progression into a more severe disease state. The present manuscript reviews several factors contributing to the costs of AD, gives an overview of available studies claiming the cost-effectiveness of current AD treatments, highlights strengths and weaknesses of the aforementioned studies, and discusses the impact of (early) identification and treatment of AD. It is concluded that there still is a need for long-term follow-up data from prospective cohort studies before the cost-effectiveness of cholinesterase inhibitors for AD can be confirmed. |
| | |
Authors:
|
Jan Versijpt |
Related Documents
:
|
18622365 - Metabolic syndrome and alzheimer's disease: a link to a vascular hypothesis? 18181435 - The seafood-nutrition-health paradigm of south pacific islanders. 22719025 - Pharmacological treatment options for hypertrophic cardiomyopathy: high time for evidence. 9391725 - Recurrent venous thromboembolic disease and factor xi concentrate in a patient with sev... 16338075 - Adult soft tissue sarcomas: conventional therapies and molecularly targeted approaches. 14745835 - The use of animal models in the study of complex disease: all else is never equal or wh... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-4-4 |
Journal Detail:
|
Title: Acta neurologica Belgica Volume: - ISSN: 0300-9009 ISO Abbreviation: Acta Neurol Belg Publication Date: 2012 Apr |
Date Detail:
|
Created Date: 2012-4-5 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0247035 Medline TA: Acta Neurol Belg Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Neurology, UZ Brussel, Laarbeeklaan 101, 1090, Brussel, Belgium, jan.versijpt@uzbrussel.be. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Vascular calcification: pathophysiology and risk factors.
Next Document: Associations of Zinc and Copper Levels in Serum and Hair with Sleep Duration in Adult Women.