Document Detail

Phaeochromocytoma in a 86-year-old patient presenting with reversible myocardial dysfunction.
MedLine Citation:
PMID:  21675829     Owner:  NLM     Status:  MEDLINE    
BACKGROUND. Phaeochromocytomas and paragangliomas are rare, mostly benign catecholamine-producing tumours of chromaffin cells of the adrenal medulla or of extra-adrenal paraganglia. Phaeochromocytoma may occur at any age, the greatest frequency being in the fourth and fifth decades. Only on extremely rare occasions does the tumour develop in the very old patients. METHODS. We are describing an 86-year-old patient with phaeochromocytoma, presenting with reversible myocardial dysfunction. RESULTS. This very old patient with phaeochromocytoma had hypertension characterized by labile blood pressure values and increased daytime blood pressure variability. This patient exhibited reversible myocardial dysfunction suggestive for "catecholaminergic cardiomyopathy", as the complication of phaeochromocytoma. After surgical removal of the tumour, recovery of left ventricular function was documented by echocardiography showing normalization of systolic function and improvement of diastolic function. CONCLUSION. Phaeochromocytomas are rare forms of secondary hypertension, but should be considered in the differential diagnosis, regardless of age, even in very old patients.
Elżbieta Szwench; Mariola P Czkowska; Krzysztof Marczewski; Anna Klisiewicz; Ilona Micha Owska; Iwona Ciuba; Magdalena Januszewicz; Aleksander Prejbisz; Piotr Hoffman; Andrzej Januszewicz
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-06-15
Journal Detail:
Title:  Blood pressure     Volume:  20     ISSN:  1651-1999     ISO Abbreviation:  Blood Press.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-14     Completed Date:  2012-04-02     Revised Date:  2012-07-26    
Medline Journal Info:
Nlm Unique ID:  9301454     Medline TA:  Blood Press     Country:  England    
Other Details:
Languages:  eng     Pagination:  383-6     Citation Subset:  IM    
Department of Hypertension, Institute of Cardiology, Warsaw, Poland.
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MeSH Terms
Adrenal Gland Neoplasms / blood*,  complications,  diagnosis,  drug therapy,  radiography,  surgery
Adrenergic alpha-Antagonists / administration & dosage,  therapeutic use
Aged, 80 and over
Blood Pressure*
Catecholamines / blood
Follow-Up Studies
Hypertension / blood*,  complications,  diagnosis,  drug therapy,  radiography,  surgery
Natriuretic Peptide, Brain / blood
Peptide Fragments / blood
Pheochromocytoma / blood*,  complications,  diagnosis,  drug therapy,  radiography,  surgery
Tomography, X-Ray Computed
Ventricular Dysfunction, Left / blood*,  complications,  diagnosis,  drug therapy,  radiography,  surgery
Reg. No./Substance:
0/Adrenergic alpha-Antagonists; 0/Catecholamines; 0/Peptide Fragments; 0/pro-brain natriuretic peptide (1-76); 114471-18-0/Natriuretic Peptide, Brain

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