Document Detail


Phaeochromocytoma: experience from a referral hospital in southern India.
MedLine Citation:
PMID:  10392893     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Phaeochromocytoma has been traditionally called the 'Tumour of Tens'. Many investigators have reported the prevalence of extra-adrenal phaeochromocytoma to be more than 10%. METHODS: All consecutive adult patients diagnosed to have phaeochromocytoma by the departments of endocrinology and surgical endocrinology of the Christian Medical Hospital, India, over a period of 10 years from 1988 to 1998, were included in the study. RESULTS: A total of 30 patients were diagnosed to have phaeochromocytoma. Extra-adrenal phaeochromocytoma accounted for 26.6% of cases, Ten per cent of cases were bilateral, 6.6% were malignant and one patient had a familial tumour (multiple endocrine neoplasia IIB). The tumours were localized pre-operatively in all patients. Multicentric extra-adrenal tumours were not found in this series. All patients except one were explored by the anterior transperitoneal approach. Persistent hypertension was noted in 30% of patients. CONCLUSIONS: Our series shows a higher prevalence (26.6%) of extra-adrenal tumours than the traditionally described 10%. With accurate pre-operative localization, a transperitoneal approach may not be necessary. The laparoscopic approach needs to be evaluated in light of these findings.
Authors:
S Mathew; B Perakath; A Nair; M S Seshadri; N Shanthly
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Australian and New Zealand journal of surgery     Volume:  69     ISSN:  0004-8682     ISO Abbreviation:  Aust N Z J Surg     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-07-08     Completed Date:  1999-07-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0373115     Medline TA:  Aust N Z J Surg     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  458-60     Citation Subset:  IM    
Affiliation:
Department of General Surgery Unit I (Surgical Endocrinology), Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Gland Neoplasms* / diagnosis,  epidemiology
Adult
Carcinoma, Medullary / epidemiology
Female
Humans
Hypertension / complications
India / epidemiology
Male
Multiple Endocrine Neoplasia / epidemiology
Paraganglioma / diagnosis,  epidemiology
Pheochromocytoma* / diagnosis,  epidemiology
Prevalence
Thyroid Neoplasms / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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