| Phadiatop testing in assessing predisposition to respiratory tract symptoms of allergic origin in athletes. | |
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MedLine Citation:
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PMID: 22554340 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objectives. To validate the use of the Phadiatop test as a predictor of allergy-associated respiratory tract symptoms (RTS) in trail runners. Methods. The incidence of self-reported RTS was documented in 16 runners for 31 days and related to the Phadiatop status and circulating markers of allergic responses (changes in concentrations of serum IgE (sIgE), differential leucocyte counts) at 8 time points before, during and after a 3-day 95 km trail run. Results. Twelve (75%) athletes, of whom 7 (58%) were Phadiatoppositive, presented with post-race RTS. A peak sIgE concentration >100 IU/ml accompanied RTS in only 4 (57%) of the symptomatic Phadiatop-positive subjects. There was no significant difference between the eosinophil and basophil concentrations of the positive and negative groups (p>0.05). One Phadiatop-negative subject presented with RTS as well as a peak sIgE concentration >100 IU/ml. Conclusion. The Phadiatop assay does not accurately predict the development of post-exercise RTS of allergic origin in trail runners. |
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Authors:
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Anton H De Waard; Edith M Peters |
Publication Detail:
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Type: Journal Article Date: 2012-03-22 |
Journal Detail:
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Title: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Volume: 102 ISSN: 0256-9574 ISO Abbreviation: S. Afr. Med. J. Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-05-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404520 Medline TA: S Afr Med J Country: South Africa |
Other Details:
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Languages: eng Pagination: 309-11 Citation Subset: IM |
Affiliation:
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Division of Human Physiology, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban. futree@ukzn.ac.za. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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