Document Detail

Phacoemulsification versus phacoemulsification with micro-bypass stent implantation in primary open-angle glaucoma: randomized double-masked clinical trial.
MedLine Citation:
PMID:  20202537     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare phacoemulsification alone and phacoemulsification with micro-bypass stent implantation in eyes with primary open-angle glaucoma. SETTING: Instituto di Fisiopatologia Clinica, Clinica Oculistica, Universita' di Torino, Torino, Italy. METHODS: In this prospective double-masked randomized clinical trial, patients had phacoemulsification alone (control group) or phacoemulsification with iStent implantation (combined group). Primary outcomes were intraocular pressure (IOP) and reduction in medication use over 15 months and IOP after a 1-month washout of ocular hypotensive agents (ie, 16 months postoperatively). RESULTS: The baseline IOP was similar between groups (combined group: 17.9 mm Hg +/- 2.6 [SD]; control group: 17.3 +/- 3.0 mm Hg) (P = .512). Three patients in the control group were lost to follow-up. The mean IOP was 14.8 +/- 1.2 mm Hg in the combined group and 15.7 +/- 1.1 mm Hg in the control group at 15 months and 16.6 +/- 3.1 mm Hg and 19.2 +/- 3.5 mm Hg, respectively, after washout; the IOP was statistically significantly lower in the combined group than in the control group at both time points (P = .031 and P = .042, respectively). At 15 months, the mean number of medications was lower in the combined group than in the control group (0.4 +/- 0.7 and 1.3 +/- 1.0, respectively; P = .007), as was the proportion of patients on ocular hypotensive medication (33% and 76%, respectively). CONCLUSIONS: Phacoemulsification with stent implantation was more effective in controlling IOP than phacoemulsification alone; the safety profiles were similar.
Antonio M Fea
Related Documents :
11442187 - Effectiveness and safety of brimonidine as adjunctive therapy for patients with elevate...
7831047 - The effect of reducing the exposure time of mitomycin c in glaucoma filtering surgery.
22955957 - Efficacy and safety of higher doses of botulinum toxin type a nt 201 free from complexi...
10376257 - Audible pops during cyclodiode procedures.
15025697 - Delayed-type hypersensitivity skin reactions due to heparins and heparinoids. tolerance...
24571397 - Factors affecting ranging behaviour in young and adult laying hens.
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of cataract and refractive surgery     Volume:  36     ISSN:  1873-4502     ISO Abbreviation:  J Cataract Refract Surg     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-05     Completed Date:  2010-05-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8604171     Medline TA:  J Cataract Refract Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  407-12     Citation Subset:  IM    
Copyright Information:
Copyright 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
Instituto di Fisiopatologia Clinica, Clinica Oculistica, Universita' di Torino, Via Juvarra 19,10100 Torino, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antihypertensive Agents / administration & dosage
Cataract / complications
Double-Blind Method
Glaucoma Drainage Implants*
Glaucoma, Open-Angle / drug therapy,  physiopathology,  surgery*
Intraocular Pressure / physiology
Lens Implantation, Intraocular
Middle Aged
Phacoemulsification / methods*
Prospective Studies
Tonometry, Ocular
Visual Acuity / physiology
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Oral acetaminophen (paracetamol) for additional analgesia in phacoemulsification cataract surgery pe...
Next Document:  Surgically induced astigmatism after phacoemulsification with and without correction for posture-rel...