| PET IMAGING OF MENINGIOMA IN CLINICAL PRACTICE: Review of literature and future directions. | |
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MedLine Citation:
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PMID: 21993189 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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ABSTRACT: Meningiomas represent about 20% of intracranial tumors and are the most frequent non-glial primary brain tumors. Diagnosis is based on computed tomography (CT) and magnetic resonance imaging (MRI). Mainstays of therapy are surgery and radio-therapy. Adjuvant chemotherapy is tested in clinical trials of phase II. Patients are followed clinically by imaging. However, classical imaging modalities such as CT and MRI have limitations. Hence, we need supplementary imaging tools. Molecular imaging modalities, especially Positron Emission Tomography (PET), represent promising new instruments able to characterize specific metabolic features. So far, these modalities have only been part of limited study protocols and their impact on clinical routine management is still under investigation. It may be expected that their extended use will provide new aspects about meningioma imaging and biology.In the present article we summarize PET imaging for meningiomas based on a thorough review of the literature. We discuss and illustrate the potential role of PET imaging in the clinical management of meningiomas. Finally, we indicate current limitations and outline directions for future research. |
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Authors:
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Jan Frederick Cornelius; Karl Josef Langen; Gabriele Stoffels; Daniel Hänggi; Michael Sabel; Hans Jakob Steiger |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-11 |
Journal Detail:
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Title: Neurosurgery Volume: - ISSN: 1524-4040 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7802914 Medline TA: Neurosurgery Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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1Neurochirurgische Klinik, Universitätsklinikum Düsseldorf, Heinrich-Heine-Universität, Moorenstrasse 5, 40225 Düsseldorf, Germany 2Institut für Medizin, Forschungszentrum Jülich, Heinrich-Heine-Universität, 52425 Jülich, Germany. |
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