Document Detail

Perventricular device closure of isolated muscular ventricular septal defect in infants: a single centre experience.
MedLine Citation:
PMID:  23253407     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To evaluate prospective single centre experience of mid-term safety and efficacy of perventricular device closure of isolated large muscular ventricular septal defect (mVSD) in high-risk infants.
BACKGROUND: Surgical closures of large mVSD in infants represent a challenge with significant morbidity.
METHODS: Between August 2008-2010, perventricular closure was attempted in 24 infants of 6.01 ± 2.37 months age and 4.27 ± 0.56 kg weight under TEE guidance.
RESULTS: The device was successfully deployed in 21/24 infants. Size of mVSD was 8.42 ± 1.46 mm (6.1-12 mm). Mean procedure time was 28.8 ± 11.7 min. The closure rate was 84% immediately and 100% at 6 months. Four patients suffered major complications: 2-died, 1-esophageal perforation, 1-persistent CHB. At 26.23 ± 6.63 months follow-up two patients were symptomatic: 1-required device retrieval, 1-died of severe gastroenteritis.
CONCLUSION: Perventricular device closure of isolated mVSD appears feasible option at mid-term follow-up and may either substitute or complement the conventional surgical technique in selected cases depending on institutional paediatric cardiac surgery performance.
Bhavesh Thakkar; Nehal Patel; Shaunak Shah; Vishal Poptani; Tarun Madan; Chirag Shah; Anand Shukla; Vaishali Prajapati
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Publication Detail:
Type:  Journal Article     Date:  2012-09-12
Journal Detail:
Title:  Indian heart journal     Volume:  64     ISSN:  0019-4832     ISO Abbreviation:  Indian Heart J     Publication Date:    2012 Nov-Dec
Date Detail:
Created Date:  2012-12-20     Completed Date:  2013-07-12     Revised Date:  2014-01-23    
Medline Journal Info:
Nlm Unique ID:  0374675     Medline TA:  Indian Heart J     Country:  India    
Other Details:
Languages:  eng     Pagination:  559-67     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.
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MeSH Terms
Echocardiography, Transesophageal
Heart Septal Defects, Ventricular / surgery*,  ultrasonography
Prospective Studies
Septal Occluder Device*
Treatment Outcome
Comment In:
Indian Heart J. 2012 Nov-Dec;64(6):568-9   [PMID:  23253408 ]

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