Document Detail

Pertussis vaccine effectiveness in reducing clinical disease, transmissibility and proportion of cases with a positive culture after household exposure in Brazil.
MedLine Citation:
PMID:  16940847     Owner:  NLM     Status:  MEDLINE    
In household outbreaks of pertussis, children <5 years of age who received at least 3 doses of vaccine had 12% less clinical disease; vaccinated cases were 63% less culture-confirmed and transmitted infection to 62% fewer contacts. Three doses of pertussis vaccine are likely to decrease circulation of Bordetella pertussis by reducing the proportion of bacteriologically positive cases and transmissibility.
Paulo N Baptista; Vera Magalhães; Laura C Rodrigues; MariaAngela W Rocha; Analíria M Pimentel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  25     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-30     Completed Date:  2006-10-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  844-6     Citation Subset:  IM    
Pediatric Infectious Diseases Service, Federal University of Pernambuco, Pernambuco, Brazil.
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MeSH Terms
Child, Preschool
Disease Transmission, Infectious / prevention & control*
Family Characteristics
Infant, Newborn
Pertussis Vaccine / therapeutic use*
Whooping Cough / prevention & control*,  transmission
Reg. No./Substance:
0/Pertussis Vaccine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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