Document Detail

Pertussis in Australia today - a disease of adolescents and adults that can kill infants.
MedLine Citation:
PMID:  17252087     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Adolescents and adults are the main reservoir of pertussis infection in Australia today. Diagnosis in these age groups can be difficult because of atypical clinical presentations and limitations of laboratory investigations. OBJECTIVE: This article discusses the common presentation of pertussis in adults and adolescents, the use and limitations of laboratory testing, and appropriate treatment and prophylaxis. DISCUSSION: The reason for treating cases and providing chemoprophylaxis for contacts is to prevent infection in infants, who account for 90% of deaths from pertussis. Treatment with the newer macrolides appears to be as effective as erythromycin and with less side effects; however, roxithromycin should not be used as its in vivo efficacy is unproven. The majority of pertussis cases will be seen in general practice - most likely during the infectious period - therefore general practitioners need to consider being vaccinated with dTpa against pertussis.
Sanjaya Senanayake
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Australian family physician     Volume:  36     ISSN:  0300-8495     ISO Abbreviation:  Aust Fam Physician     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2007-01-25     Completed Date:  2007-03-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326701     Medline TA:  Aust Fam Physician     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  51-6     Citation Subset:  IM    
The Canberra Hospital, The Australian National University Medical School, Australia.
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MeSH Terms
Australia / epidemiology
Bordetella pertussis / pathogenicity
Infant, Newborn
Whooping Cough* / diagnosis,  drug therapy,  epidemiology,  physiopathology

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