Document Detail

Pertussis is common in nonvaccinated infants hospitalized for respiratory syncytial virus infection.
MedLine Citation:
PMID:  17414394     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: There is some evidence that Bordetella pertussis can cause co-infection with respiratory syncytial virus (RSV). SUBJECTS AND METHODS: RSV etiology was studied by antigen detection in 117 infants <6 months of age, who were hospitalized for respiratory tract infection during an RSV epidemic. B. pertussis etiology was studied by polymerase chain reaction in those 88 in whom parents or nurses reported cough. RESULTS: RSV was found in 91 (78%) infants and B. pertussis in 9 (8%) infants. In 7 cases, there was mixed RSV-pertussis infection. In retrospective analysis, RSV and mixed RSV-pertussis cases could not be separated by clinical characteristics. CONCLUSIONS: Co-infection caused by B. pertussis was present in 8% of infants, aged <6 months, who were hospitalized for RSV infection. To avoid under-diagnosis, pertussis should be considered in all nonvaccinated infants with lower respiratory tract infection.
Matti Korppi; Johanna Hiltunen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  26     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-06     Completed Date:  2007-06-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  316-8     Citation Subset:  IM    
Department of Pediatrics, Kuopio University Hospital, Kuopio, Finland.
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MeSH Terms
Bordetella pertussis / genetics,  isolation & purification
Cough / etiology
Disease Outbreaks
Infant, Newborn
Respiratory Syncytial Virus Infections / complications*,  epidemiology,  virology
Respiratory Syncytial Virus, Human / isolation & purification
Respiratory Tract Infections / complications*,  epidemiology,  microbiology,  virology
Whooping Cough / complications*,  epidemiology,  microbiology

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