Document Detail


Perturbationless calibration of pulse transit time to blood pressure.
MedLine Citation:
PMID:  23365873     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pulse transit time (PTT) often shows strong correlation with blood pressure (BP) and may therefore represent a means for achieving continuous, non-invasive, and cuff-less BP monitoring. However, construction of the subject-specific curve needed to calibrate PTT to BP conventionally requires simultaneous measurements of PTT and BP during an experimental perturbation that varies BP over a significant range. We propose a technique for perturbationless calibration of PTT to BP. This technique constructs the calibration curve from central and peripheral BP waveforms by exploiting the natural pulsatile variation in the waveforms via a nonlinear tube-load model. We conducted initial testing of the technique in animals by applying it to the waveforms during a baseline period and then predicting mean BP during subsequent major hemodynamic interventions via PTT calibrated with the resulting curve. The bias in the mean BP error was 4.9 mmHg, while the precision in this error was 7.6 mmHg.
Authors:
Mingwu Gao; Ramakrishna Mukkamala
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2012     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2012  
Date Detail:
Created Date:  2013-01-31     Completed Date:  2013-08-06     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  232-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure*
Blood Pressure Determination / instrumentation,  methods,  standards
Blood Pressure Monitors*
Calibration / standards
Humans
Models, Cardiovascular*
Nonlinear Dynamics*
Pulse Wave Analysis* / instrumentation,  methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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