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Perspective: nonalcoholic fatty liver disease and cardiovascular risk.
MedLine Citation:
PMID:  23298957     Owner:  NLM     Status:  In-Data-Review    
Nonalcoholic fatty liver disease (NAFLD) has emerged as a clear risk factor for cardiovascular risk. Through its association with metabolic syndrome including insulin resistance and type 2 diabetes, NAFLD certainly has strong indirect associations with cardiovascular risk. Recent population studies have strengthened the association with prevalent coronary heart disease. Investigative cardiology has shown that NAFLD is also associated with markers of subclinical atherosclerosis, such as diminished endothelial function and carotid artery intima-media thickening. Though causality between NAFLD and cardiovascular disease can only be tested in a clinical trial, these recent findings do emphasize the need to develop strategies including nutritional that may prevent NAFLD.
Paul J Nestel; Ronald P Mensink
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current opinion in lipidology     Volume:  24     ISSN:  1473-6535     ISO Abbreviation:  Curr. Opin. Lipidol.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010000     Medline TA:  Curr Opin Lipidol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1-3     Citation Subset:  IM    
aBaker IDI Heart and Diabetes Institute, Melbourne, Australia bDepartment of Human Biology, School for Nutrition, Toxicology and Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.
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