Document Detail


A Perspective on Recurrent Vertigo.
MedLine Citation:
PMID:  23796949     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The recurrent nature of the 3 most common vestibulopathies suggests a recurrent cause. Histopathology in temporal bones from patients with these syndromes - vestibular neuronitis (VN, n = 7), Ménière's disease (MD, n = 8) and benign paroxysmal positional vertigo (BPPV, n = 5) - shows focal degeneration of vestibular nerve axons and degenerated nearby facial nerve meatal ganglion cells. Transmission electron microscopic confirmation of intracytoplasmic viral particles in surgically excised vestibular nerves from patients with VN and MD support a viral etiology in these vestibulopathies. Antiviral treatment of these syndromes in a series of 211 patients with a 3- to 8-year follow-up resulted in complete control of vertigo in VN (88%), MD (90%) and BPPV (60%).
Authors:
Richard R Gacek
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-6-21
Journal Detail:
Title:  ORL; journal for oto-rhino-laryngology and its related specialties     Volume:  75     ISSN:  1423-0275     ISO Abbreviation:  ORL J. Otorhinolaryngol. Relat. Spec.     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-6-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0334721     Medline TA:  ORL J Otorhinolaryngol Relat Spec     Country:  -    
Other Details:
Languages:  ENG     Pagination:  91-107     Citation Subset:  -    
Copyright Information:
Copyright © 2013 S. Karger AG, Basel.
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, University of Massachusetts Medical School, Worcester, Mass., USA.
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