| Personalized medicine: a pediatric perspective. | |
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MedLine Citation:
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PMID: 19814914 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of pediatric personalized medicine is to uniquely combine genetic variation with developmental stage and environmental exposure to provide a tailored preventive, diagnostic, and therapeutic regimen. Recent advances in genomic research have identified many genetic variants that may be related to allergic and inflammatory disease and therapeutic response. These include variants involved in immune response, barrier proteins, and medication response. Current evidence also suggests that the effect of genetic variation often depends on the developmental stage of a child and environmental exposure such as infection or tobacco smoke during a specific stage. Personalized medicine is a new and exciting field with the potential to significantly improve medical care for children and adults. |
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Authors:
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Daniel Arnold; Bridgette L Jones |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current allergy and asthma reports Volume: 9 ISSN: 1534-6315 ISO Abbreviation: Curr Allergy Asthma Rep Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-09 Completed Date: 2009-12-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101096440 Medline TA: Curr Allergy Asthma Rep Country: United States |
Other Details:
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Languages: eng Pagination: 426-32 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Asthma
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genetics*,
physiopathology,
therapy* Child Child Development Environmental Exposure Genetic Predisposition to Disease* Humans Individualized Medicine / trends* Pediatrics / trends* Social Class |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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