| Personalized medicine for individuals with Down syndrome. | |
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MedLine Citation:
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PMID: 21807541 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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As the cost of whole genome analysis decreases, we have the opportunity to explore the interactions of various gene changes in an individual that lead to their particular phenotype. This will provide the ability to move from the epidemiologic study of groups, in which, the individuals are treated collectively and homogenously, to personalized medicine, and a model in which the individual is recognized and treated as a distinct entity. We will be applying personalized medicine to individuals with Down syndrome in order to understand and develop biomarkers for increased risk of co-morbidities. Personalized medicine will change the "culture of intractability" of Down syndrome. |
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Authors:
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Linda L McCabe; Edward R B McCabe |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-19 |
Journal Detail:
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Title: Molecular genetics and metabolism Volume: - ISSN: 1096-7206 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-8-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9805456 Medline TA: Mol Genet Metab Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Linda Crnic Institute for Down Syndrome, University of Colorado School of Medicine, USA; Center for Bioethics and Humanities, University of Colorado School of Medicine, USA; Department of Pediatrics, University of Colorado School of Medicine, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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